Because intrinsic disorder correlates with important regulatory functions, we asked how these bacteria could exist without IDPs by studying transcription factors, known to harbor a lot of function-related intrinsic disorder.
To better discriminate and understand the intrinsic and environmental correlates of changing aquatic ecosystems, we untangle in present study how the effects of a low-dosed fungicide on daphnids (via different exposure routes) becomes modified by increasing temperature and the presence of a predator.
We show that this measure of intrinsic drug property correlates very well with in vitro-measured antiviral activity, whereas experimentally measured IC50 does not.
These Fe0 materials necessarily depict disparities in their intrinsic reactivity but correlating the reactivity to any material characteristic properties, including the nature of alloyed elements, was proven an impossible task (Richardson and Nicklow 2002; Miehr et al. 2004; Noubactep et al. 2009a; Btatkeu-K et al. 2013; Birke et al. 2015; Li et al. 2016).
We found that the model scores (hereafter referred to as intrinsic nucleosome occupancy) correlate significantly with in vivo nucleosome occupancy in CD4+ T-cells [8] (R = 0.28; Figure 1A; range of R is 0.20 0.33 per chromosome).
The basal phenotype classification by Sorlie's intrinsic gene set correlated strongly with basal cytokeratin IHC (concordance 76%, p = 0.0011).
Based on the site of first relapse data for liver, lung, brain, and bone, Kaplan Meier plots were generated, and we determined that intrinsic subtype was correlated with site of relapse (Fig. 2, Supplemental Fig. 3).
Here, local fluctuations and the intrinsic disorder propensities correlate with the evolutionary rates, whereas global dynamics (where proteins undergo large-scale motions involving multiple residues moving together in a collective manner) reflect evolutionary variance.
We show that in vivo occupancy positively and significantly correlates with intrinsic nucleosome occupancy, indicating that intrinsic histone-DNA sequence preferences play a role in dictating nucleosome arrangement in vivo.
A new model is proposed for rapid evaluation of the degree of long-chain branching in polymers, which correlates the intrinsic viscosity and the molecular weight.
