Sentence examples for intriguing locus from inspiring English sources

The CCL3L1 gene represents a particularly intriguing locus for study, most notably for its implication in HIV AIDS susceptibility [ 1], but also because this region demonstrates several layers of complexity.

The other CpG island that was not differentially methylated in the TCGA tumors is associated with the zinc-finger protein ZCCHC14, which is an intriguing locus, as SNPs in that gene have been associated with nicotine dependence [ 38].

Subsequently, numerous genetic association studies made the DAOA/G30 gene complex one of the most intriguing susceptibility loci for the major psychiatric disorders.

The DAOA/G30 (D-amino acid oxidase activator) gene complex at chromosomal region 13q32-33 is one of the most intriguing susceptibility loci for the major psychiatric disorders, although there is no consensus about the specific risk alleles or haplotypes across studies.

Thus, it is intriguing to identify a locus on LG6 in F. vesca subsp. bracteata that also affects sexual expression.

The DEFA1A3 locus is intriguing in that it falls within a region of high linkage disequilibrium, despite its high variability in copy number (n = 3 16); hence, the mechanisms responsible for changes in copy number at this locus are unclear.

It is intriguing that the GRB10 locus was associated with fasting glucose level in European populations [ 25] but showed no evidence of association for T2D in African Americans [ 26].

The association of FAMA and RBR with the SPCH locus is intriguing, as in normal development SPCH is required for initiation of the stomatal lineage and is essential for robust expression of all stomatal genes so far reported (MacAlister et al., 2007; Pillitteri et al., 2007; Kanaoka et al., 2008).

The EGFR locus was intriguing for several reasons, because we had initially visualized a reproducibly significant hypermethylation 'spike' at the 7p11.2 region, which contains the EGFR gene as well as several other nearby gene targets on the list of hypermethylated gene targets.

Note, however, that the proposed centromere for scaffold 7 lies next to the rDNA locus, an intriguing position given the opposite location of the centromeric pole and the nucleolus in interphasic nuclei of S. cerevisiae (reviewed in Zimmer and Fabre 2011).

We find a signature of positive selection that is strong and widespread for all but one of the loci and identify intriguing evidence of an association between two loci and neonatal brain mass in two non-primate clades.