Titles are chosen for their literary value, historical importance, intriguing backstory, original illustrations, and scarcity.
Thus, the described independent origin of netrins provides an intriguing confirmation of the importance of domain architecture for protein function.
So how ARRB1 exactly interacts with the BECN1 core complex remains an unanswered and intriguing question of fundamental importance.
This variation is intriguing given the central importance ascribed to laminin-binding by DG for its function as a cell-ECM adhesion receptor.
Although the results do not support increased efficacy of combined treatment, they provide intriguing evidence of the importance of RAS expression in determining patient response and tumour growth potential and suggest that components of the RAS could be used as biomarkers to aid in patient selection.
It will be intriguing to determine the importance of these highly polymorphic genes in diseases such as autoimmunity and cancer where copy number variation of the region in which they are embedded has already been shown to be important [ 28, 29].
There were several differentially expressed genes related to vision and eye development, which is intriguing because of the importance of visual communication in the genus Polistes, although P. metricus is not known to use visual cues for individual recognition [ 52, 53].
This is intriguing and may have functional importance, as prolonged CREB activation has been correlated with enhanced neuroprotection in previous studies [65], [70].
These intriguing findings point to the importance of the timing of NO production and apoptotic stimuli in determining the actual anti- or pro-apoptotic effect, even if steady state conditions favor cell survival, in agreement with our previous observations [50] [52].
The "co-incidental" convergence of the autonomously carried out immunological investigations by us and clinical studies by others on GOLPH2 strongly hints at the potential importance of this intriguing molecule.
