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All cultures struggle with intractable mental illnesses with varying degrees of compassion and cruelty, equanimity and fear.
In recent years, many psychiatrists have come to believe that the last, best chance for some people with severe and intractable mental problems is psychosurgery, an experimental procedure in which doctors operate directly on the brain.
It is interesting that the Nova series on PBS chose the most food-focused month of the year to air a very candid program about eating disorders, its victims, its probable causes and the newest treatments for what psychiatrists rank among the most intractable mental problems and, for anorexia at least, the deadliest.
Such is the case in Amish communities (8), where treatment for psychiatric disease may only occur in response to crises like intractable mental anguish, emergent hospitalization, violence, or the threat of suicide (8).
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The severity of the disease is highly variable, ranging from mild skin manifestations to intractable epilepsy, mental retardation, and autism [ 8].
Malformations of cortical development frequently result in varying combinations of intractable seizures, mental retardation, cerebral palsy, and focal neurological deficits [ 50].
Most affected individuals display severe neurological manifestations – such as intractable epilepsy, mental retardation and autism – that are intimately associated with peculiar CNS lesions known as cortical tubers (CTs).
Most readers will be familiar with the tectonic ideological stresses that have caused such visible upheaval in the field today: the repudiation of many Freudian tenets, the rise and undeniable success of new medications to treat the most intractable forms of mental illness and the more impersonal, hurried approach that often comes with the dispensing of drugs.
Eating disorders (EDs 1), and specifically anorexia nervosa (AN), have long been characterized by unusually staggering complexity, even in comparison with other intractable functional (inorganic) mental disorders.
Among the long and seemingly intractable list of determinants, mental health and social and emotional wellbeing loom as critical priorities.
Also, three nuclear families with GLUT1 DS were reported to date, in which the phenotype between family members varied from intractable epileptic seizures with moderate mental retardation to controllable epileptic seizures with mild mental retardation (Brockmann et al., 2001; Ho et al., 2001; Klepper et al., 2001 b ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com