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It is biologically plausible that ketamine could be an effective treatment for intractable headache.
CDH is a type of intractable headache that is seen frequently.
References. 1. Silberstein S, Dodick D, Pearlman S (2010) Defining the pharmacologically intractable headache for clinical trials and clinical practice.
The proposal of intractable headache in migraine introduced the concept of failure of at least four classes of preventative drugs for the first time [20].
Refractory migraine is included in ICHD-2 [10] and ICHD-3 beta [11] but criteria for intractable headache have only recently emerged [12].
We used no placebo arm in this study because it was immoral to use no drug in the subjects with intractable headache.
Similar(38)
Every few weeks, he would totter into his doctor's office and beg for something, anything, to ease his intractable headaches.
In this light, CS appears to underlie intractable headaches.
Criteria employed to define intractable headaches were given more than ten years ago (1).
ONS is safe and efficacious in the treatment of medically intractable headaches conditions.
Occipital nerve blocks (ONB) have generated great interest among headache specialists recently because of their potential to treat many types of intractable headaches [1, 2].
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