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Many of us teachers live for such moments, when for whatever usually intractable combination of factors, we help inspire our students to open their eyes a bit wider, take ownership of their education, and connect their academic learning to the larger world outside their hermetic bubble of tests and grades and program requirements.
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Bowers et al. (2004) suggested a method to derive more general logical rules by exhaustive enumeration, an approach that is computationally intractable for combinations of more than two COGs.
For example, for 50 000 SNPs and 1000 genes, we have roughly 5 × 10 (= 50 000 × 1000 × 1000) combinations, making scanning over all possible combinations intractable.
TCR-γ gene is recommended to the routine analysis, whereas TCR-β gene has potential in combination toward intractable cases.
One species, H. mana, proved to be intractable with this primer combination and was amplified using a novel primer, C1-J-1580, as the forward primer.
This is most urgent for children with SCID [ 13], who generally present with failure to thrive from early infancy in combination with intractable diarrhea.
The calculation of all possible n-way combinations may even become computationally intractable when the number of combinations is high enough.
However, considering all possible causal combinations is intractable.
Malformations of cortical development frequently result in varying combinations of intractable seizures, mental retardation, cerebral palsy, and focal neurological deficits [ 50].
Evaluating many possible combinations can computationally intractable.
While mathematically rigorous, enumerating null space vector combinations can become intractable for large-scale problems, similar to EFM analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com