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One of the most intractable bottlenecks for practical assembly of next - generation short reads is how to process repetitive fragments from complicated genomes, especially eukaryote genomes.
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Existing methods are primarily limited by computational bottlenecks, as optimization is often practically intractable.
The main bottleneck to ab initio protein structure calculation methods is that the size of the search space is intractable.
Unfortunately, corruption remained intractable.
It's intractable.
Some bottlenecks remain.
Bottlenecks on Purpose Q.
But the alternatives look intractable.
Corruption remained an intractable problem.
Burdens are no longer intractable.
Damon is intractable.
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