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Perhaps the deal could be saved if Frank said sorry to the Russian people for sullying their motherland with the intolerable activities of a now-dead gay-rights campaigner.
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For example, a large number of potential spare regimens will lower the bar of intolerable disease activity for treatment changes considerably.
Similarly, the New York Press Club and other groups that represent journalists said Monday that "what the police did on November 15th to suppress coverage of their activities was intolerable".
This experience made it clear that it is possible to redirect enormous amounts of productive resources from military to civilian activity without intolerable economic disruption.
Intolerance is intolerable.
It is, therefore, understandable why many patients consult only when symptoms become intolerable as a consequence of high disease activity.
If the heat is intolerable, stay indoors when you can and avoid activities in direct sunlight or on hot asphalt surfaces.
New therapeutic options aside, the perception of disease activity (and when it is deemed intolerable) changes over the years.
[However] I think it would be intolerable to have to keep a detailed account of all such activities and how would they be ranked relative to each other".
Some therapies may achieve antitussive activity, but at the expense of unpleasant or intolerable side effects.
More likely, it is a hotbed of collusion and anti-competitive practices that would be intolerable were it not for the veil of official secrecy surrounding INSA's activities.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com