Similarly, different amounts of CRP (0 250 μg/mL) were added into the CRP-free serum, as the PCT concentration in the mixture was fixed at 5, 50, and 500 ng/mL separately.
In contrast, one previous meta-analysis that included 16 studies was performed by the conversion of estimates into thirds of the CRP distribution (18).
Karakiewicz et al. [ 24] were able to show in a group of 313 patients that the incorporation of the CRP value into the UISS scoring systems for patients with localized RCC might improve its prognostic significance.
After its stratification into the three groups (CRP ≤4, 4 10, and >10 mg/l) the discriminative power and prognostic significance of the CRP value became even more evident.
Approximately half of all patients fell into the 'borderline' CRP 20-500) group with an antibiotic prescription rate of 56.6%, and just over half of these (53%) were delayed prescriptions, representing the highest rate of delayed prescriptions in these 3 subgroups.
The CRP level dropped to 9.5 mg/dl after the operation and two weeks later, the CRP level decreased into normal levels (0.2 mg/dl).
In the first set of the multiple linear regression analyses, the CRP data were transformed into log CRP to achieve normal distribution and used in unadjusted and adjusted analyses with log UAE for the total sample (n = 693) and for each racial/ethnic group.
The CRP normalized completely.
CRP/Alb: the CRP (mg/L -albumin (g/L) ratio.
The CRP-level, stratified into two subgroups (CRP ≤5 vs. >5 mg/l), correlated significantly with muscle invasive tumour stage (36.4 vs. 78.9%; p<0.001), the risk of presenting nodal disease (4.5 vs. 26.8%; p=0.002) and distant metastasis (2.3 vs. 16.9%; p<0.016).
Finally, we a priori divided our groups into 'high CRP' and 'low CRP,' instead of outcome variables.
