Sentence examples for into the coregulation from inspiring English sources

To gain additional insight into the coregulation of Cluster 3-D, the MEME system was used to identify highly conserved motifs within the regions 500 base pairs upstream from all of the genes in the cluster [ 55].

All three algorithms performed poor, partially because they were originally developed and tuned towards searching for motifs in the coregulation or the combined coregulation-orthology space.

Success rates observed in the coregulation space were treated as baseline levels.

Figure 4 displays the difference between the F-value obtained from searching in the combined coregulation-orthology space and the F-value obtained from searching in the coregulation space only.

In the combined space we tested under which conditions adding orthologs improved the baseline success rate observed in the coregulation space.

Variation in a variety of other behaviors has been attributed to changes in the coregulation of suites of genes [ 61- 65].

For the experimental setup we simulated datasets for the coregulation space, the orthologous space and the combined coregulation-orthology space.

As for the coregulation space, we also tested for the combined space the effect of missing motif sites in the coregulation direction.

Under such conditions, adding orthologous information to the coregulation space can improve the results.

In this section we assessed to what extent adding orthologous information to the coregulation space improves motif detection.

For each pair, we contrasted the coregulation observed in E. coli with a null averaged value obtained with randomized networks (Materials and methods and text S1 section 2).