In this paper we present FunMod, an innovative Cytoscape version 2.8 plugin that is able to mine undirected protein protein networks and to infer sub-networks of interacting proteins intimately correlated with relevant biological pathways.
Part of IMRA's success in this regard seems to have come from Albert Rakoto-Ratsimamanga's combination of foreign training and experience with deep local knowledge, which may suggest the value of leadership which is intimately familiar with relevant cultures.
How different from the Sage and in Easington, where many in the audience knew the relevant landscape intimately, and where some were watching their parents or grandparents or, in a few cases, their younger selves on screen.
Although the presacral corridor to the sacrum is generally considered an anatomic safe zone, access through this region can be safely exploited only if the surgeon is intimately familiar with the relevant pelvic anatomy.
The homing mechanism is well documented and appears to be particularly relevant to GIR1 because its activity is intimately related to the expression of a HE mRNA (H Nielsen, in preparation).
The autophagy/lysosomal pathway has been linked to all of these disorders, and the observation that LRRK2 is intimately involved in this cellular process may be relevant to its role numerous human conditions, further emphasising the need to clarify the mechanisms that link LRRK2 and the autophagy-lysosomal pathway.
Identifying relevant genetic variants or single nucleotide polymorphisms (SNPs) in genes intimately linked to various neurobiological pathways, whose alteration may contribute to suicidal behaviour, may provide insight into the etiological processes that underlie suicidal behaviour and identify novel biological therapeutic targets.
We observed that some GIs were intimately associated with the physiology and ecology of the microorganisms but we also found some relevant conserved genes in theory linked to the core genome.
To exemplify the potential for Citrus improvement of the information included in the EST collection, two gene families with relevant agronomic interest were selected and analyzed in detail: the ammonium transporter family intimately related to plant nutritional efficiency and the glycoside hydrolase family 20, implicated in sugar synthesis in fruit.
