However, after thorough reports of their existence, survival, activation, and differentiation there are still many questions to be answered regarding the intimate mechanism of tissue regeneration.
The intimate interplay of tissue-specific signaling pathway activation in AMD with age may shed new light into other age-related diseases and eventually aging itself [ 36, 37].
We only observe disparities in the functional role of Cxcl5 in males and females in response to pro-inflammatory stimuli where a temporal relationship between production of Cxcl5 and extent of neutrophil infiltration into tissue intimates a causal relation.
It mediates the metabolic exchanges of the developing individual through an intimate association of embryonic tissues and of certain uterine tissues, serving the functions of nutrition, respiration, and excretion.
The direct intimate contact of bone tissue to the surface of an implant is unique to the technology of cement-less fixation and is the key to preventing the effects of implant loosening.
Successful dental and orthopedic implants require the establishment of an intimate association with bone tissue; however, the mechanistic explanation of how biological systems accomplish osseointegration is still incomplete.
We noted that iRBC were in intimate contact with placental tissue components and that hemozoin was widely spread in maternal blood spaces of infected placentas.
These established less intimate contact with gland tissue, and in the rare instances that parasites adhered to microvilli, they did not appear to attach tightly to epithelial cell surface structures (Fig 7C F).
This could be caused by an additional boost of the immune response due to more intimate exposure of lymphoid tissue to tumor cells than in stage II tumors.
Based on the phenotypical features of DCs, including the intimate association with lymphoid tissue, the presence of intraepithelial B-lymphocytes and the lack of goblet cells, DC has been suggested to derive from M-cells of the gut-associated lymphoid tissue [ 1].
