Sentence examples for intestinal role from inspiring English sources

To explore the intestinal role of LIN-35, we conducted a genome-wide RNA-interference-feeding screen for suppressors of lin-35 ; slr-2 early larval arrest.

Consistent with a possible intestinal role, we detected transcript upregulation of the JH target Kruppel homolog 1 (Kr-h1) (Jindra et al., 2013) in guts of mated females.

JH has been shown to sustain ovarian maturation through pleiotropic actions on adipose and reproductive tissues (Flatt et al., 2005), but its intestinal roles remain to be established.

Such intestinal roles would be consistent with the finding of isolated insulin-producing secretory cells in the digestive tract of other invertebrates and protochordates (Sherwood et al., 2005).

This observation, coupled with two studies regarding Sjögren's syndrome (SS; Ewert et al., 2010; Nguyen et al., 2008), suggests a possible extra-intestinal role for GPA33 in barrier function.

Both these transcription factors play important roles in intestinal function and often co-occupy binding sites (Verzi et al., 2010, 2013).

The intestinal epithelial role of Hnf4α is of less importance when disrupted during post-embryonic development of the gut [11].

7 9 However, whereas Wnt/β-catenin signalling is well known to play multiple roles in intestinal tumorigenesis, the role of Notch in this process remains unclear.

However, our microarray findings implicated Hunk in intestinal tumourigenesis, a role we wished to elucidate further.

Despite the fact that PAs and their acetylated derivatives are a prerequisite for cellular metabolism and considered to be essential for proliferation and differentiation of the rapidly renewing intestinal mucosa, their role during intestinal mucosal inflammation is less clear [ 33].

The finding that ROS and NF-κB both play important roles in intestinal tumor initiation indicates a role for inflammation in this process.