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In the 3/6 patients with differential hypoxia, these interventions were unsuccessful and a veno-arterial-venous ECMO was implemented.
While initial surgical interventions were unsuccessful, aggressive treatment with intracameral and oral moxifloxacin resulted in a good visual outcome.
Four interventions were unsuccessful at improving presenteeism in their specific employee populations and work settings (Additional files 4 and 5).
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When assessing the intervention from a participant perspective, these costs are important to capture as they often help explain why promising interventions are unsuccessful and/or have very low reach.
Although valuable in their own right, such methods also offer the opportunity to enrich more traditional approaches to assessing interventions, helping to explain why some interventions are unsuccessful, or why they seem to work effectively in some contexts but not in others.
The intervention was unsuccessful.
Thus, for example, a publication that reports limited adherence to an intervention or describes that the spread of the intervention was unsuccessful receives credit for reporting on adherence and spread.
Finally, if the intervention is unsuccessful, this study will determine what factors contributed to a negative outcome, as well as any unexpected consequences to persons with MND or their families.
While the intervention was unsuccessful, the study was well-described and executed and highlighted important factors (e.g. use of culturally salient interventions delivered by ethnic psychotherapist) that may facilitate successful interventions in future research in the target population of the study.
Alternatively, if the intervention is unsuccessful, it will be possible to assess each of the processes in the hypothesised causal chain in order to determine whether the intervention was not delivered as intended or whether the assumed causal relationships were incorrect.
Despite the success of HAPA in predicting health outcomes for those with type 2 diabetes mellitus, the intervention was unsuccessful in changing healthy eating or any of the other measured variables, and alternative low-cost health interventions for those with type 2 diabetes mellitus should be explored.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com