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Here we highlight the interventions we believe hold the most promise for policy leaders.
However, given the variety of data collection methods used, and the efforts made to identify interventions, we believe the examples reported are representative of the interventions being undertaken.
On the other hand, since this is an observational study which does not involve the performance of invasive tests or pharmacologic interventions, we believe this will also facilitate recruitment and patient inclusion.
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As these criteria influence the characteristics of the study population and the number of patients that will be eligible for the trial, and thereby the chances of finding an effect of the intervention, we believe that also in the choice of entry criteria explicit estimates of the number of eligible patients should be made.
For this type of intervention, we believe that the pros of using a pragmatic approach outweigh the cons.
Though we did not compare changes in the ethical environment and climate between pre- and post-intervention, we believe that the improvement in patient outcomes has reflected these achievements.
Nevertheless, given the abrupt reduction in readmission rates with the onset of the intervention, we believe it unlikely that the results we observed were caused by external secular trends.
Given our finding that a large number of referred patients may benefit from psychological intervention, we believe that health care providers should familiarize themselves with symptoms and signs that may indicate psychological difficulties (see Table 1).
As part of a consistent and clinically applicable intervention, we believe it would be crucial to not only limit the development of secondary damage following TBI but also to activate major neuroprotective pathways.
Although several studies explored the effect of decision aid interventions on treatment decision making as a proxy for the effectiveness of the intervention, we believe that patient attitudes toward the decision making process may be a more important indicator of shared decision making effectiveness as the ultimate treatment choice may depend on several individual factors.
Because we offered foods during the ad libitum phase that were not offered during the intervention, we believe that this specific selection for savory high-protein foods is a result of compensatory mechanisms that are induced to restore adequate protein status.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com