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Information on medication use during the evaluations and interventions was obtained from parents by written communication and included data on the physicians who prescribed the medication.
Finally, a direct priority ranking of various interventions was obtained.
Adherence to the each of the active interventions was obtained by class attendance and biweekly home practice logs.
The sequence of interventions was obtained from a computer-generated random number list in permuted blocks provided through the Australasian Kidney Trials (AKTN) network.
The evidence of efficacy for all interventions was obtained from RCTs identified by means of a systematic literature review, which is a strength from an internal validity point of view.
After the interview, information about CVD screening and interventions was obtained from the participant's computerised GP notes, using a standardised form which was completed by the researcher (who visited the practice) or by the practice staff.
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Interventions were obtained from a meta-analysis.
Standardisation of the interventions is obtained by teaching the involved physiotherapists in an instructional course.
Second, the direct medical costs of the interventions were obtained from different sources.
Prior to the test patients were encouraged to reach maximal exhaustion, while during exercise no further motivational interventions were obtained.
Additional data regarding health care consumption (exact date and content of visits and interventions) are obtained from medical records.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com