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The proportion of patients with previous digital ulcer complications and interventions was broadly similar in the anti-scleroderma-70 subgroup and the ACA subgroup; the most marked exception was for surgical amputation, which occurred almost twice as frequently in patients with ACA (14.6%) compared with anti-scleroderma-70-positive patients (7.9%) (table 3).
Similar(59)
Interventions were broadly categorised into two categories.
Interventions were broadly categorised as either technical (n = 11) or interpersonal (n = 9).
Each term in the scope was defined (see online supplementary file 1); interventions were broadly any environmental factor in the International Classification of Functioning Disability and Health ICFF).
In short, just because a disease might arise from many mechanisms, mechanisms that could even be pragmatically unknowable for given individuals, interventions can still be possible, if such interventions are broadly based.
Interventions were broadly defined as health or social services delivered in a community setting in any country (e.g., services received as an outpatient in a primary care setting).
Although this should be tested in future research, such an approach is expected to be as effective as the present one focusing on patients with diabetes because 1) mindfulness-based interventions are broadly applicable, and 2) previous studies have found these interventions are effective in other chronic disease patient groups (41).
Once the intervention was broadly agreed upon, we defined the goal of the capacity strengthening intervention, as well as an overarching framework that linked the goal to activities, outputs, and outcomes.
Currently, percutaneous coronary intervention is broadly applied in patients with significant coronary artery stenosis, and this reperfusion strategy has profoundly improved cardiovascular outcomes in the past two decades.
However, penfluridol is also a depot and because we aim to test if our intervention is broadly applicable we decided to include both patients with oral penfluridol and injections.
While the principles of intervention are broadly applicable, solutions are unique to the work context (e.g., worker socio-demographics and occupational skill levels, type of workplace, presence or absence of a union).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com