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The information letter included information about the frequent occurrence of anxiety disorders, the availability of effective preventive interventions, the possibility to assess their risk status, and the procedure.
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Since the data was based on a randomised intervention, the possibility that the intervention had an effect on GDM incidence cannot be denied.
When using a post-/pre-test difference to define improvement after an intervention, the possibility of regression towards the mean cannot be excluded.
Since these results were based on a small, uncontrolled sample and conducted by those who had developed the intervention, the possibility of bias is a legitimate concern.
In adopting a more intensive early intervention, the possibility of incurring adverse events may be higher compared with more relaxed treatment strategies.
In doing so, these interventions offer the possibility of including gait retraining earlier in rehabilitation programming.
The preponderance of NI among HBW babies with congenital anomalies may reflect surgical interventions, or the possibility of immunocompromise.
Another advantage of schools as the setting for prevention interventions is the possibility to reach a large number of people at the same time.
At most these 12 interventions offered the possibility to gain an additional 560,000 QALY, for about €640 per capita in additional costs over the entire time horizon.
Web-based interventions have the possibility to reach large numbers of people, and have repeatedly proven to be effective in changing various health behaviors and their determinants [ 17– 17].
These results further point to the balance of benefit to the amount of time spent completing 'tasks' related to ICT interventions and the possibility of over-use engendering detrimental preoccupations related to symptoms and mood state.
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