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All of the interventions studied were found to reduce significantly the risks of diarrhoeal illness.
Overall, there was some discrepancy between the types of interventions studied and the types of supportive services available to and sought by cancer patients.
A third possibility that attempts at translation are made prematurely (or badly), before an intervention is well understood, seems less likely to account for failed translation of the many very promising preclinical interventions studied in multiple clinical trials.
The interventions studied vary widely in their comprehensiveness, but a lack of both standardized outcome measures and controlled evaluations means that it is difficult to compare different interventions, either within or across sectors.
The interventions studied were exercise training in 2 trials, nutritional supplementation in 3 trials, combined exercise plus nutritional supplementation in 5 trials, pharmaceutical agents in 5 trials, multi-dimensional programs in 2 trials, and home-based services in 3 trials.
We find that demand side interventions alone are less effective than using only supply side interventions or a combination of both; the single most effective intervention is implementing a patient reminder system to reduce the number of no-show patients; and that all interventions studied are subject to significant diminishing returns.
Future work is needed to develop the rectal antibacterial interventions and to study the best ways to make the rectal interventions studied here both available and used in the communities that need them.
This was the case for all of the interventions studied.
The interventions studied fall into four broad categories representing different approaches to suicide prevention.
Most essential components of the interventions studied are not clearly established.
While several of the interventions studied show promise, there are some caveats.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com