With regards to the management of LBP, guidelines recommend that patients are initially offered conservative management in the form of education and exercise/manual therapy/acupuncture or a combination of a physical and psychological treatment if individual interventions prove ineffective [ 2].
Nevertheless, the intervention proved ineffective in reducing weight loss during radio chemo therapy.
The approach we have used (ie, the MRC Framework approach) followed recognition that complex interventions too often proved ineffective in expensive randomised trials and that, whatever the outcome of their evaluation, little could be concluded about how or why they had (or had not) worked.
However, the lispro intervention in this trial proved ineffective in significantly altering intraday variability, and the trial, stopped early for futility, and was of a relatively short duration.
Almost a century ago, radical interventions such as surgical hemispherectomy proved ineffective.
At the end of the Either/Or tour, some of his close friends staged an intervention in Chicago, but it proved ineffective.
Accordingly, randomized control trials (RCTs), in particular if double-blind, are taken as trumping other evidence, a view supported by clinical experience from other areas, in which many widely promoted clinical interventions have proven ineffective or harmful.
The multifaceted and thorough design of the complex peer-intervention is also a strength, even if eventually it proved ineffective.
This may explain why educational interventions that simply inform about the conventional medical view have proved ineffective.
The AU force has proved ineffective but a bigger or more robust intervention, by America or any other country, is not expected; this week Condoleezza Rice, America's secretary of state, called in vain for UN peacekeepers to be sent.
