For the intervention of exercise or behavioural, or multi-modal interventions, a supplemental data abstraction form was provided to summarize falls outcomes as these were deemed relevant for this particular set of interventions.
H5: Adherence to exercise during the 9-month unsupervised follow-up period will be greater with an integrated intervention than with an intervention of exercise alone.
H1: A 12-week integrated intervention of exercise and PCST will be more efficacious in improving pain and self-reported physical function than a 12-week intervention of either PCST or exercise alone immediately following the intervention.
H6: An integrated intervention will be more cost-effective than an intervention of exercise or PCST alone when costs are compared and related to the effects of the intervention at 52 weeks.
H2: An integrated intervention of exercise and PCST will be more efficacious in improving pain and self-reported physical function than either PCST or exercise alone at 32 weeks and 52 weeks.
The current study included 136 patients who completed the baseline visit and had cardiovascular imaging prior to the intervention of exercise and dietary modification and comprised of 84%% of the overall LANDMARK 3 study population.
Physiotherapy interventions consisting of exercise and manual therapy appear beneficial in several areas as an adjunct therapy in HIV management.
When studies investigated multiple interventions, intervention arms inclusive of exercise where combined, including interventions separating aerobic and resistance exercise.
This effect seemed to be independent of hormonal group, weight loss after intervention, amount of exercise per week, and intervention modality (see Additional file 1 : Table S4).
Assessments took place before intervention, consisting of exercise training, revascularization or amputation.
