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Variability between studies in study perspective, time horizon, setting, comparators, included costs and interventions makes it difficult to compare and assess cost-effectiveness between alternative strategies.
However, the fact that they are often used in combination with preventive and educational interventions makes it difficult to understand the efficiency of the treatments per se, as well as their reproducibility in other settings.
Lack of evidence from direct comparison between active interventions makes it difficult for clinicians to choose the most effective treatment for patients [ 49].
The lack of process evaluations of such interventions makes it difficult to ascertain whether their poor results are because of design failures or implementation weaknesses.
The growing number of older adults globally, as well as workforce issues and the expense of interventions, makes it important to develop rational, targeted, and cost-effective risk-reduction strategies.
· The lack of documentation of key distribution interventions makes it difficult to support the widely-held belief (in Omaheke) that provision of "the basics" encourages learners to remain in school.
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Several aspects of our intervention should increase its efficiency and credibility, relative to other interventions, making it uniquely suited for widespread dissemination.
Health policy models provide measures of the effectiveness and costs of complex health care interventions making it possible to compare different policies.
Kraul believes "the high cost" ― around $10 billion over 16 years ― "and the U.S. politics militating against foreign interventions" make it hard to replicate the plan.
The availability of a wide range of interventions made it possible to provide a highly individualized package of interventions.
Community-based strategies in LMICs, however, often combine several different interventions, making it impossible to disentangle their individual effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com