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In the Look AHEAD (Action for Health in Diabetes) study, patients randomized to intensive lifestyle interventions lost 8.6% of their body weight from baseline after 1 year, and this weight reduction was accompanied by decreases in glycated hemoglobin (A1C) (−0.6%) and fasting plasma glucose (FPG) (−21.5 mg/dL) [ 7].
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The Saudis, whose supply of anti-tank missiles to the mainstream opposition led to the Russian intervention, lost interest late last year.
The trial's reported success is because those who received the intervention lost an extra 1.4kg (3.1lb) after 12-months compared to those who received the control.
Participants in the HELP PD LWL intervention lost an average of −7.1 kg (7.3%) at 12 months.
Some women who were lost to the second visit and test after the intervention (lost to follow up), re-entered the study at the postpartum examination.
At 1 year, participants in the weight loss program intervention lost 8.2% of initial weight compared with a 2.5% weight loss in the control group.
A recent meta-analysis [ 29] which evaluated the impact of e-therapeutic interventions on weight reduction presented very relevant conclusions: the individuals who received the intervention as a complement to standard intervention lost significantly more weight, while the individuals for whom the intervention was a substitute of the traditional intervention lost significantly less weight.
Diabetes patients with lower educational levels (no college degree) who participated in lifestyle intervention lost more weight or waist circumference than those with higher levels of education (≥ college degree) [ 45].
A secondary analysis of data from the Look AHEAD trial found that nearly 40% of severely obese participants in the intensive, DPP-like lifestyle intervention lost ≥10% of initial weight at 1 year [ 8], and 26% were able to maintain this weight loss at year 4 [ 11].
Successful intervention does not win votes; failed intervention loses buckets of them.
If not, then sales interventions are lost opportunities to strengthen the organization.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com