The largest divergence of opinions was recorded for the criterion "Comparative intervention limitations" (SD: 1.1).
Health professionals and academic researchers provided a lower score for the performance of the sensor on the criteria 'Comparative intervention limitations' (−0.2) compared to all participants.
In contrast, differences of 2 and 3 points (on a scale of 0 to 3) were observed for "Type of medical service" (SD: 0.8) and "Comparative intervention limitations" (SD: 0.7), respectively.
Major value contributors were the criteria 'Severity of disease' (0.19; SD, 0.07), 'Size of affected population' (0.17; SD, 0.06), 'Comparative intervention limitations' (0.17; SD, 0.07), and the 'Improvement of efficacy/effectiveness' (0.18; SD, 0.09).
Appraisal of the pulmonary heart sensor revealed that the major contributors to the value of this innovation were 'Size of population' , 'Severity of disease' , and 'Comparative intervention limitations' , highlighting the health need for the management of heart failure.
Although clearly informative, these interventions have limitations owing to the gradual onset of PtdIns 3,5 P2 depletion.
However, the variety in severity of symptoms, types of interventions, and limitations of trial methodology and reporting, suggest that the findings must be interpreted with caution [ 28, 12].
In common with other real life dietary interventions the limitations of this study are the inability to fully blind or control for both energy load and osmolality.
In spite of the huge demand for such evaluated interventions, some limitations to this study have to be mentioned: Since this project is a systemic public health intervention, the implementation of a Randomized Controlled Trial (RCT) is not feasible.
However, due to the substantial heterogeneity among the herbal interventions and limitations of methodological quality of the included trials, it is not possible to recommend any specific CHMs for recurrent miscarriage.
