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There are many therapeutic interventions in use that have not been evaluated in well-designed randomized controlled trials (RCTs).
In the absence of region-wide vaccination coverage, systematic study of severe HFMD is needed, including proper assessment of the current interventions in use.
[ 3, 4] Advances in medical knowledge and treatment capabilities often take too many years to reach patients; many therapeutic interventions in use are not supported by evidence of effectiveness.
The extent to which these needs generate a response may often be a political decision but also reflects the personal motivation of the stakeholders concerned [ 5]. "The majority of health care interventions in use today are not proven in terms of efficacy and cost effectiveness.
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Many psychological interventions are in use today based on the efficacy demonstrated in waitlist controlled trials.
Which recommended interventions are in use?
Other interventions currently in use with children include psycho-pharmacological treatments, play therapy, psychological debriefing and testimony therapy [ 17, 20, 23, 26, 34- 39].
Therefore many interventions are in use to minimize pressure on bony prominences, such as repositioning and different kinds of pressure relieving devices [ 23, 27, 28].
We wanted to evaluate the effectiveness of interventions in current use, i.e. published since 1990, as established in well-designed randomized studies.
In fact, I challenge any candidate to find a nook or cranny that has not already been set aside for academics or intervention and in use all day long -- including broom closets.
The intervention was in use for approximately 2 years, from September 2011 to November 2013.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com