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Since combining experiments into a single analysis when different interventions have similar effects increases sample size and, thus, power, whereas combining them when the interventions have different effects increases the within-group variance and, thus, avoids the risk of reporting false positive results.
This has shown that the interventions have different effects on the theoretical constructs.
When two interventions have different profiles, both patients and surgeons have a preferable intervention.
In particular, multiple interventions meta-analyses may be helpful both when a broad class of interventions is synthesised and when broadly similar interventions have different combinations of components.
Such RCT's could be used to explore whether such interventions have different effects on externalizing behavior between different genetic subgroups (similar designs have been previously used see Bakermans-Kranenburg and Van IJzendoorn 2015).
The likelihood that CR operates by many mechanisms in addition to decreased mTORC1 signaling is further supported by a recent publication showing that the two interventions have different metabolic outcomes in aged mice (Miller et al., 2014).
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Whilst all of the studies reported outcomes to at least 12 months the interventions had different durations.
The two psychosocial interventions had different delivery formats: CSP focused on individual carers while RYCT focused on groups of people with dementia and their carers.
Therefore, if after the intervention is implemented, the group that received the intervention has different outcomes — is more or less healthy, or has higher or lower medical expenditures — we know that these differences were caused by the intervention.
A statistically significant interaction meant that the intervention had different effects according to the baseline score for the outcome variables.
Each intervention had different arrangements for employing and training people with personal experiences of mental health issues to work as Peer Workers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com