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For each safety problem defined, a list of treatments was composed, both for previous ("last decade") and current safety programs, where safety interventions are ranked according to their appearance frequency and, for each item, relevant countries are mentioned.
Where more than two interventions are being compared, the ICER is calculated according to the following process: first, the interventions are ranked in terms of cost, from least to most expensive.
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Next, all interventions were ranked in order of their probability of selection.
Interventions were ranked in terms of costs from the cheapest to the most expensive.
All the interventions were ranked, initially according to the cost-effectiveness ratio based on societal costs, and subsequently on the ratio including health care costs only.
The ranking probabilities were defined as cumulative probabilities with each intervention being ranked.
Figure 4 presents the probability that each intervention is ranked as 1st, 2nd, 3rd etc. out of all interventions compared for each outcome based on estimated treatment effects and associated uncertainty.
A simple linear additive evaluation model was used to calculate overall scores, and interventions were rank ordered according to their 'cost-value' ratio (estimated by dividing the costs of an interventions by the overall score).
The interventions with the lowest incremental cost effectiveness ratio are ranked highest and are economically most attractive.
A given task was considered complete only if all four interventions had been ranked, directly or indirectly.
The intervention that was ranked as the highest priority was to focus on recruiting and retaining health care workers in rural hospitals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com