These analyses also suggested that different modes of intervention delivery, interventions utilizing pedometers, interventions of greater intensity (median ≥14 contacts), and inclusion of a supervised PA and exercise component were not associated with clinically significant improvements in HbA1c.
However, clinical trials to date have produced mixed results potentially attributed to timing of interventions (end stage) and utilizing outcome markers such as weight which is confounded by hydration, cytotoxic therapies, and serum cytokines.
Working with Alaska Native and Latino communities, people with serious mental illness, alcohol and drug problems, or heart disease, and jobseekers and the unhoused, Dr. Prochaska's research combines stage-tailored interventions with pharmacotherapy and utilizes interactive expert system interventions and social media.
This was a group intervention following a protocol created by one of the authors (RS) consisting of a mix of existing group interventions and exercises utilized in a variety of therapeutic schools.
In particular, provider audit and feedback did not impact glycemic control [ 14, 15] The most effective interventions are targeted and utilize case management, expansion of clinic team member roles, and/or patient self-management initiatives [ 14- 20].
Information systems, especially those involving multiple stakeholders, profoundly limit the capability of traditional generic methods of analysis to develop and utilize interventions.
However, several efficacious familial interventions have been developed and utilized within other patient groups.
Several studies, as well as MND practice guidelines, suggest the need to develop and utilize interventions that will support hopefulness, a sense of meaning, and dignity in order to alleviate psychosocial and existential distress in persons with MND [ 7, 8].
Further research requires longitudinal and intervention studies, utilizing multi-level design methodologies and objective measures of environmental attributes.
One study [ 14] was a palivizumab dose escalation trial and utilized separate intervention arms of 3, 10, and 15 mg/kg.
