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These attitudes are deep seated and will not be modified by solely developing web-based interventions: a broader strategy will be required to embed DESIs into routine practice.
Practice-based research is needed to improve evidence-based practice in health promotion and for evaluation of such interventions, a broader range of evaluation designs need to be considered [ 10].
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The single unitary health utility index derived from the EQ-5D will enable comparison across a range of interventions, a broad scope of health issues and diseases, and may also capture "unanticipated effects" not built into the PDQ-39 [ 36, 37].
A recent review article suggests the number of studies testing interventions for patients with multi-morbid disease has increased, but the findings showed that organizational interventions with a broader focus and patient-specific interventions not linked to care delivery had little impact on health outcomes [ 7].
The weaker study designs associated with population-targeted interventions increase the risk of being unable to reproduce health outcomes when implementing interventions on a broader scale.
We searched for publication and all related biases (because this search strategy was also used for a systematic review on the effectiveness of interventions with a broader scope [ 4]), so that we could identify relevant articles on well-known as well as new interventions to prevent publication bias (Additional file 1).
Conversely, employment impacts have generally been smaller for interventions with a broader focus or where the supports did not substantially differ from existing services.
Organisational interventions with a broader focus, such as case management or changes in delivery of care, seemed less effective.
Rehabilitative interventions include a broader range of factors affecting outcomes of care [ 19] and there is demand for further outcome dimensions according to different intervention goals.
Firstly, successful interventions contained a broader range of components that worked on barriers and facilitators to anti-retroviral drug adherence considered important by people infected with HIV-1.
Yet, patients might benefit from interventions with a broader remit that help to establish and maintain wider contacts in the community.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com