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More generally, if the EIR in a setting is relatively high then an intervention will need to be highly successful to ensure that no increase in clinical disease occurs, whilst if the EIR is in the range in which a peak in clinical disease incidence is predicted (approximately 30 ibppy in this model) then even a moderately effective intervention will reduce clinical disease incidence.
The intervention will need to be targeted to the exact phenotype of the frailty identified.
Each principle of the intervention will need to be interpreted for the situation, which we term here as 'amendments'amendments
Parental beliefs and understanding are crucial determinants of infant feeding behaviour, therefore any intervention will need to take account of these views.
Additionally, the intervention will need to tackle particular problems in rural areas, and among different population, ethnic and socio-economic groups.
Clearly, the function of GSK3β in LSC biology is context dependant, and therapeutic intervention will need to be sensitive to the particular molecular lesions and self-renewal pathways involved in any particular myeloid malignancy.
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Interventions will need to go beyond the lone participant and include shared decision making models that incorporate family members and friends.
Clearly more needs to be learned about patient and unit factors that are related to psychological difficulties, and tailored interventions will need to be appropriate for individuals with cognitive impairments.
And the right interventions will need to be funded to make best use of the resources available.
However, such interventions will need to reach 3.8 million people facing food insecurity and 1.5 million people displaced by the conflict.
Combination prevention interventions will need to be feasible to deliver and attractive to diverse MSM populations.
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responses will need to
actions will need to
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intervention was necessary to
intervention will be required to
intervention will be required
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intervention would be required to
intervention is essential to
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