We describe the design of the MERGE trial, a cluster randomised trial, to evaluate the effect of an intervention to optimise TB/HIV service integration on mortality, morbidity and retention in care among newly-diagnosed HIV-positive patients and newly-diagnosed TB patients.
This enhanced understanding will orient decision-makers regarding avenues of intervention to optimise the efficacy and effectiveness of healthcare services.
PtiO2 levels of below 15 mm Hg require immediate intervention to optimise cerebral tissue oxygenation (Fig. 4).
Earlier identification of those very preterm infants at risk of adverse neurodevelopmental and motor outcomes provides an additional period for intervention to optimise outcomes.
In order to develop a theory-based intervention to optimise adherence to phosphate binding medication, there is a need to first understand the factors associated with nonadherence that could be addressed.
If beneficial, the novel rehabilitation strategy of utilising outpatient exercise classes during a later rehabilitation phase would provide a feasible and potentially cost-effective intervention to optimise the physical well-being of the large number of people undergoing TKR.
