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Modulation of CMA function in PD by miRNA silencing might represent a suitable target for drug intervention to modify the deleterious effects of impaired protein handling.
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Integrated Flood Management (IFM) aims to harmonize human activities and flood risks through appropriate interventions to modify the water regime, and adaptation of human behavior thereby reducing such risks.
The authors argue that improving the use of pharmaceuticals through interventions directed only to consumers may have a small impact and suggest that in order to obtain meaningful changes it might be necessary to design interventions to modify the behavior of all the actors in the medication cycle (manufacturers, health professionals, retailers, consumers and governments).
As it has been reported that vertigo and dizziness were the greatest contributors to the burden of disability in the aged population, 9 screening for dizziness and vestibular dysfunction, and parallel interventions to modify the associated factors, are required in a rapidly ageing society.
The working group recommends early intervention to modify repetitive movements of the shoulder or hand/wrist during work, work that demands much or prolonged power of the upper arms, hand-arm vibration (high vibration and/or prolonged exposure) during work, and work in a non-ergonomic shoulder position.
We aimed to assess whether an internet-delivered intervention to modify handwashing would reduce the number of RTIs among adults and their household members.
Intervention to modify lifestyle has been termed "the most important single action to prevent type 2 diabetes mellitus" (2).
The existence of this biogeochemical divide separating the Antarctic from the Subantarctic suggests that it may be possible for climate change or human intervention to modify one of these without greatly altering the other.
Research on the correlates of sedentary behaviour among adults is needed to design health interventions to modify this behaviour.
Researchers interested in elaborating interventions to modify this prescription behaviour could use this study results accordingly.
Likewise, the Oviedo Convention provides Article 13, which states: "An intervention seeking to modify the human genome may only be undertaken for preventive, diagnostic or therapeutic purposes and only if its aim is not to introduce any modification in the genome of any descendants".
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