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The main predictors of the model include intervention indicator (0 = control versus 1 = intervention), data collection time points, and the interaction term between intervention indicator and time points.
The treatment effects will be evaluated by testing the significance of the coefficient of intervention indicator and an interaction term of time and the intervention indicator.
The intervention indicator variable (pre-PEP vs post-PEP) will be used as the main fixed effect.
The mean, minimum, and maximum of the intervention indicator and all of the control variables are listed in Table 1.
These results are reported in Table 2, which contains the marginal effects of the control variables and the intervention indicator.
There was no significant effect of centre and no significant interactions between protocol specified variables and the intervention indicator.
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For each intervention, indicators were identified and agreed up on.
The intervention indicators were derived from the findings of previous studies [ 1- 6].
Task teams found denominators the most technically challenging issue for measurement of intervention indicators and have identified a list of denominator options for testing wherever possible.
Additionally, these indicators were computed over the entire intervention period (referred to as intervention indicators) and for differences between steps/day reported during the first two weeks of the intervention and the remaining weeks (3 27; referred to as change in intervention indicators).
This theory is supported by data from a survey of the level of attainment of intervention indicators in England, which showed that several quality indicators were rapidly achieved by most practices in 2004-5, the year the intervention was implemented.
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