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The goal of this model is to facilitate answering important questions related to intervention efficacy, including: 1) Was the intervention efficacious?
The stepped wedge design was chosen for pragmatic reasons, because it was impossible to introduce the interventions into all clusters simultaneously 29; this also enabled the team to ensure that all children in the study area would eventually receive the intervention, avoiding the ethical issue of leaving children in a study area without the intervention (efficacious drugs) that work.
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However, adherence success varied substantially across the studies, with only about 25% of interventions efficacious.
Integrative psychosocial interventions combining efficacious interventions from the alcohol and PTSD fields have shown promise.
The larger study [ 26] found the intervention was efficacious in improving self-efficacy for coping with cancer, regulating negative mood, and reducing cancer-related post-traumatic symptoms.
2) For whom was this intervention most efficacious?
There are demonstrated benefits of early detection, timely intervention, and efficacious treatment.
If the intervention is efficacious, this could potentially influence clinical practice and health policy.
Reduction in RBC transfusion requirement is a good indicator that a hemostatic intervention is efficacious.
The present study indicates that the investigated intervention is efficacious in enhancing circulating levels of these nutrients in AD.
Although the intervention was efficacious in promoting weight loss, the lack of influence on QOL was contrary to the hypothesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com