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For reviews where word limits may prevent detailed reporting, authors are encouraged to provide intervention details in online supplementary materials, which is now an option in the majority of journals.
Authors were also contacted for missing intervention details or data.
The intervention details (D) are sent to the GUI Agent (E).
Many intervention details also remained missing, limiting the amount of data available to perform meta-regression.
While 28 authors responded to these requests and provided missing intervention details, 14 did not respond to numerous reminders.
However, it has been estimated that, especially in non-pharmacological interventions, the published literature typically includes incomplete intervention details.
This problem has been compounded by incomplete reporting of intervention details in a substantial proportion of cardiac rehabilitation trials [11, 12].
Once this has been carried out, an intervention details message is formed (C) and this is sent to the GUI Agent DD).
Two reviewers independently extracted data concerning participant characteristics, intervention details (including participants' lithium exposure immediately preceding the trial), and outcome measures from the included studies.
Additionally, by using an exhaustive process to contact trial authors for missing intervention details, we were able to provide a more complete picture of exercise training than has ever been previously examined.
The following quality items were used to assess the methodological quality and risk of bias in the studies [[30],[31]]: eligibility criteria, adequacy of sample size, reporting of randomization, reporting of blinding, avoiding selective reporting, description of intervention details, description of outcome measures, description of adverse effects, and adequacy of data analysis.
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