There were no significant differences in level or in trend change between the two sub-periods of the intervention (adjustment period and effective intervention period).
As part of the intervention refinement, adjustments to the protocol were made throughout the study, and inclusion criteria were revised.
The evaluations of the pilot study in phase II permitted refinement of the intervention, and adjustments were made before we considered it ready for clinical trial purposes.
In addition to survey content and intervention mix, adjustments to the data collection schedule were made to ensure that data collection occurred at the times when the interventions were offered (e.g., when the VMMC program was being implemented).
It has been recommended that interdisciplinary teams, formal education, various interventions e.g. non pharmacological interventions, environmental adjustments and specialized units could provide better options for care of older people at risk for delirium [ 49].
The first is a practical one and concerns educational and curricular interventions and adjustments in medical studies with an aim to foster moral reasoning.
Indeed the correlation would differ according to outcome, setting, intervention, covariate adjustment and also sampling [ 5, 9, 10].
Risk factor intervention, medical adjustment, physical and psychological assessments were offered at baseline and after 3, 6 and 12 months.
The sensitivity analysis, which included data of the 2007 survey, confirmed the major effect of the intervention after adjustment for the same pattern of predictors.
We found no statistically significant between group differences for any of the secondary outcome measures at the end of the intervention after adjustment for baseline scores.
