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If two segments of the same state were separated by an intervening sequence of ≤5 probes and ≤10 kbp, both segments and the intervening sequence were called as a single variant.
DNA synthesis at one primer is directed toward the other, resulting in replication of the desired intervening sequence.
Our studies show that the intervening sequence in SIGA vector RNA is partially spliced.
We have previously shown that the poly(A) polymerase (PAP) gene of Trypanosoma brucei is interrupted by an intervening sequence.
The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group.
However, after one round of retroviral replication, the intervening sequence should be removed by the cellular machinery and the therapeutic gene will be selectively expressed in target cells.
One intervening sequence (IVS) within between the hypervariable region 1 and the conserved region 2, designated as IVS-p, was found to be unique to poultry feces.
The excised intervening sequence of the Tetrahymena ribosomal RNA precursor mediates its own covalent cyclization in the absence of any protein.
This site-specific process requires precise sequence recognition at the boundaries of an intervening sequence, but the mechanism of this recognition is not understood.
The Tetrahymena intervening sequence (IVS) has been inserted into the gene for the alpha-donor fragment of beta-galactosidase in a recombinant plasmid.
The intervening sequence RNA excised from the ribosomal RNA precursor of Tetrahymena forms linear and circular oligomers when exposed to a heating-cooling treatment in vitro.
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CEO of Professional Science Editing for Scientists @ prosciediting.com