The multivariate logistic regression analysis identified three time factors including intervals of collapse-to-call, call-to-first CPR, call-to-arrival to patients as independent factors associated with 1-month survival.
Analyses of the time intervals from collapse to the start of bystander CPR and from collapse to the call to EMS were limited to those with an interval of ≤60 min. We measured outcomes in terms of 1-month survival and favorable neurological status at 1 month in the three age categories.
The intervals from collapse to start of bystander CPR and from collapse to the call to EMS were significantly shorter among cases with a non-family bystander than those with a family bystander.
Shorter elapsed time intervals from collapse to initiation of CPR have been established as important contributors to favorable outcomes following OHCA [ 38- 40].
The aim of the present study was to investigate the impact of the time interval from collapse to return of spontaneous circulation (CPA-ROSC) in cardiac arrest patients and the types of patients who will benefit from therapeutic hypothermia.
In another article in Critical Care in 2010, Kagawa and colleagues [ 16] compared the impact of the time interval from collapse to ROSC and the impact of therapeutic hypothermia for the different time intervals.
The time of onset of cardiac arrest was only recorded in cases of witnessed cardiac arrest, and the estimated duration of cerebral anoxia was defined as the interval from collapse (presumed time of cardiac arrest) to first resuscitation attempt by emergency medical services.
After CA, the most relevant factor contributing to recovery is the time interval between collapse and initiation of resuscitation efforts and the return of spontaneous circulation (ROSC).
CI: confidence interval; CPA-ROSC: time interval from collapse to return of spontaneous circulation; CPR: cardiopulmonary resuscitation; MTH: mild therapeutic hypothermia; OHCA: out-of-hospital cardiac arrest; ROSC: return of spontaneous circulation.
Time interval from collapse to return of spontaneous circulation (CPA-ROSC) cut-off value of 29 minutes in the hypothermia group and 15 minutes in the normothermia group had the highest combined sensitivity and specificity, with accuracies of 75.4% and 92.8%, respectively.
The mean time interval between collapse and onset of resuscitation was 2.3 ± 2.1 minutes.
