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Recurrence rate and time interval to recurrence were comparable to those of well-matched historical controls.
We used this information to calculate the median of the interval to recurrence.
The overall mean interval to recurrence after the operation was 14.2 ± 13.9 months (range, 0.8 65.2 months).
An 11-gene signature associated with the activated BMI1 was identified, and it reliably predicated shorter interval to recurrence and poor prognosis in 11 types of human cancers [ 39].
In conclusion, we found that the clinicopathologic characteristics and time interval to recurrence did not differ between histologic types.
Higher expression of TK1 in prostate carcinoma was associated with a shorter interval to recurrence and development of metastasis [ 14].
Similar(51)
In comparison with the previously published studies (Fox et al, 1975; Schumer and Cannistra, 2003), in our series the follow-up is longer and, as such, is able to detect more delayed recurrences, thus justifying the longer time interval to recurrences that we reported in comparison with other series.
The clinical records of the patients, i.e., site, TNM status, treatment and follow-up data (length of time since surgery and disease-free interval time to recurrence or death from surgery) are reported in Table 1.
Disease-free survival time (DFS) was defined as the interval from surgery to recurrence.
Our findings show a strong association between PTEN deletion and a shorter time interval to PSA recurrence.
In a similar study Glinksy et al. developed an 11-gene signature that was predictive of a short interval to disease recurrence, distant metastasis, and death after therapy in cancer patients diagnosed with many types of cancer [ 14].
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