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For 57% (93/163) of drugs, the label rate was within the Bonferroni-adjusted 95% confidence interval of the proportion of patients from PLM who reported nausea (Fig. 4).
Accounting for parental genotype at each AFLP locus, we estimated goodness of fit to Mendelian expectations by calculating the confidence interval of the proportion of individual offspring in which a given allele was present.
CI 95%: 95% confidence interval of the proportion.
Abbreviations: CI, confidence interval of the proportion; DS, decreased susceptibility; R, resistant.
The 95% confidence interval of the proportion of apparent heterozygosity, as calculated using an exact binomial test for the entire set of marker data, is 0.946 0.986.
The equivalence was considered statistically significant at two-tailed if the 95% confidence interval of the proportion difference lies within the pre-specified equivalence margin of ± 5%.
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Equivalence was established if the lower bound of the 95% confidence interval on the proportion of concordant positive responses was greater than or equal to 70%.
For CEF responses, the 95% C.I. on the difference in response rates was (−0.4%, 7.8%); the lower bound of the 95% score confidence interval on the proportion of concordant positivity calls was 89.5%.
Specifically, for CMV responses, the 95% C.I. on the difference in response rates was (−1.5%, 1.5%) and the lower bound of the 95% score confidence interval on the proportion of concordant positivity calls was 97.2%.
We considered the crude rate to be a binomial proportion, and estimated standard errors of the proportion, and 95% confidence intervals of the proportion accordingly.
The proportion of patients who met criteria for hypoxemia from the entire sample population and for each age group was calculated and reported with 95% confidence intervals of the proportion.
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