Additionally, states can be defined by applying previously described methods for assessing drug exposure, such as single or multiple-interval measures of medication gaps [ 12, 13].
They also define a related class of measures they term continuous multiple-interval measures of medication gaps (or CMG measures) that attempt to quantify theoretical gaps in medication usage.
Using VA pharmacy records, we utilized a continuous multiple-interval measure of medication gaps (CMG) to assess the proportion of time in prior year that patient did not possess the prescribed medications; CMG ≥20% is considered clinically significant non-adherence.
Steiner and Prochazka [ 7] refer to this and related indices as part of a larger class of measures they call continuous multiple-interval measures of medication availability (or CMA measures for short).
Age, gender, language, education, rater, interval between assessments, baseline number of medications, medical comorbidity, severity of medical illness, acute physiology score, and cognitive functioning were not associated with short-term depression stability.
29 There should be adequate intervals between the escalations of medication during titration, to prevent overdosage and side effects from accumulative doses.
The frequency of four visits per year is based on the fact that in the guideline measurement of lithium serum levels is recommended at 3 6 months intervals and that prescription of medication is allowed for a maximum duration of three months.
In this study, all children received up to three doses of medications at interval of 20 min till they achieved predefined spirometric parameters.
Although some parents (27.1%) reported administration of medication at four hourly intervals, 4.7% reported more frequent intervals.
MPR informs patient medication adherence by providing the ratio of the number of days of medication supplied within a refill interval to the number of days in a specified refill interval [ 16, 17].
