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The nonlinear fractional-order quadratic integral equation on an unbounded interval is difficult to solve.
Even the >80 ng/mL interval is difficult to visualize in Figure 5 (blue shading; not always present at a given age).
Autolysis-associated histological changes are well recognised in PM samples, with variation between tissue types, but quantitation of such changes in relation to factors including cause of death and PM interval is difficult.
However, as the generation interval is difficult to observe the serial interval is usually used, i.e. the expected time between symptom onset in the index case and symptom onset in its secondary case [ 11, 17].
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Cases in which a p value would be preferable to a confidence interval are difficult to find.
Moreover, arranging to conduct the telephone interview at regular two month intervals was difficult.
Because generation intervals are difficult to observe, we used the serial interval as a proxy for the generation interval (18 ) and assumed equivalence.
Due to the unusual scale of NNTs their confidence intervals are difficult to describe if the effect is not significant [ 22].
A particular problem challenging all studies within this area of research is that time points and hence time intervals are difficult to measure precisely.
Although this format is convenient for browsing a single genomic region or base-pair position through an online genome browser, large collections of genomic intervals are difficult to rapidly search.
Traditional fertility measures, such as calving-to-first service (CFS) and calving-to-conception (CC) intervals, are difficult to use in genetic improvement programmes because: 1) fertility is expressed late in life, 2) reproductive records are lacking and/or have poor quality, 3) traits are not normally distributed [ 6], which complicates the analysis, and 4) have low heritability (<5%) [ 4].
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