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The energy mean free path time was introduced as a factor to characterize the lower limit of a decay interval for fitting an initial decay slope, and to determine the initial point of a decay curve.
The red vertical dotted line indicates the start time of the target interval for fitting the aftershock models.
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Both TOG domains bind with comparable affinity to T238A and WT tubulin. 1 Σσ confidence intervals for fitted affinities are provided in parentheses.
Our proposed method is similar to that discussed in Mukherjee et al. with a couple of differences: 1) we conducted weighted curve fitting to favor future predictions; 2) we calculated the confidence interval for the fitted curve rather than fitting two additional curves for the lower and upper quartile data points.
The 95% confidence interval for the fitted value of y for a particular value of x, say xp, is again calculated as fitted y ± (tn-2 × the standard error).
The confidence interval for the RV was calculated and the Ki67-DIA-2 values were tested for fitting the confidence interval.
The shaded areas show a 95% confidence interval for the fitted models.
The 95% confidential intervals were calculated for fitted parameters using method described by Motulsky (see Supplementary Materials online).
Therefore data was extracted from in vitro and ex vivo studies, as well as clinical studies in patients at various stages of CD, and 95% confidential intervals were calculated for fitted parameters using method described in [ 49] (see Additional file 1: Table S2).
Non-linear regression (SPSS 15.0) was used to fit the upper part of equation 2 to the data and obtain 95% confidence intervals for the fitted constants c and k.
We have used the 'Delta method' to calculate confidence intervals for the fitted models41.
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