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For continuous functions f the value of f(t), for t in the interval, changes only slightly, so it must be very close to f(t).
The MRI study showed interval changes from the baseline examination performed 15 months prior.
Small QT interval changes are easy to miss and the regulators therefore expect the relevant studies to be very precise.
"Your heart beat interval changes as you get tired and this is all about detecting those changes," says Steve Cliffe, the firm's business development director.
The effects of Q-Tc interval changes resulting from different anesthetic agents on morbidity and the incidence of arrhythmias during anesthesia warrant further investigation.
When we consider the whole 15-year interval, changes within industries are the most important ones right after the observed changes in the distribution of occupations.
The total data amount of the OFA does not change as the generation time interval changes because ((1/Delta {t}) cdot p_{mathrm{f}}) is always constant.
The time interval changes from a longer to a shorter duration from summer to winter, which is obvious due to the day-night differences during summer and winter.
Galvin et al. introduced the MCI test which assesses the listener's ability to detect and identify interval changes between successive tones in a short sequence [4].
Since there are presently no established accurate possibilities of testing the propensity to torsade induction during clinical drug development, the regulators require drug-related QT interval changes to be thoroughly investigated with almost all new pharmacological agents.
To report the clinical implications of interval changes in choroidal neovascularization (CNV) size measured by indocyanine green (ICG) angiography in neovascular age-related macular degeneration (AMD) patients undergoing intravitreal bevacizumab therapy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com