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Survival time was calculated as the interval between interview date and date of death or until the date of December 31, 2007 if those older persons were still alive.
No notable differences in symptoms were reported based on the difference in the interval between onset date and date of completing the follow-up survey.
The retrospective and prospective time interval between index date and dispensation date was shorter for women than for men, with variations according to medication category (Table A1).
In total, 2000 controls, frequency-matched to cases by age (within 1 year), sex and follow-up time (interval between start date and index date), were randomly selected from the pool of eligible controls.
The median interval between return date and diagnosis date was 8 days (range 0 28 days; interquartile range 4 18 days).
Overall survival (OS) was defined as the interval between the date of diagnosis and the date of death/last date known to be alive.
The progression-free survival (PFS) was defined as the time interval between the date of surgery and the date of progression/recurrence or date of last follow-up.
The PFS was defined as the time interval between the date of surgery and the date of progression/recurrence or date of last follow-up.
Overall survival (OS) was defined as the interval between the date of surgery and the date of death or the date of the last known follow-up visit.
OS was defined as the time interval between the date of surgery and the date of death, or the date of last follow up for those who were alive at the end of the study.
In these models, the time variable was the interval between the date of enrolment and the date of last follow-up or date of death, whichever occurred first.
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