Sentence examples for interstitial fluid exchange from inspiring English sources

The system facilitates continuous cerebrospinal fluid and interstitial fluid exchange and plays a key role in removing waste products from the rodent brain.

Cortisol concentrations in plasma and interstitial fluid may not necessarily run in parallel and blood plasma to interstitial fluid exchange may be often compound specific.

The glymphatic system is a recently defined brain-wide paravascular pathway for CSF and interstitial fluid exchange that facilitates efficient clearance of interstitial solutes, including amyloid-β, from the brain.

The ependyma provides a bidirectional barrier and transport system for cerebral spinal fluid (CSF) and interstitial fluid exchange (Del Bigio, 2010; Johanson et al., 2011; Roales-Bujan et al., 2012), helping to keep the brain toxicant free and in physiologic balance (Johanson et al., 2011; Roales-Bujan et al., 2012).

For a broader description of the latter topic, the reader is referred to reviews on transcapillary fluid exchange and interstitial fluid volume regulation [ 2- 9].

This brain-wide clearance pathway, which has been termed the glymphatic system, has been shown to facilitate clearance of solutes from the brain, with cerebrospinal fluid entering along periarteriolar channels where there is solute exchange with interstitial fluid, and then exiting via para-venous pathways [ 18].

While CR extravasation across a relatively intact blood brain barrier is likely to be minimal in the deep WM, a similar assumption in periventricular regions, where CR in the CSF may exchange with interstitial fluid at a disrupted ependymal lining, is less clear.

The brain's cleansing process, called the glymphatic system, clears waste when cerebrospinal fluid (CSF) filters through the brain and exchanges with interstitial fluid (ISF).

SjB (cm2), which denotes the total abluminal endothelial surface area exposed to the interstitial space of tissue j, and γ, which is the endothelial surface area recruitment factor (see Methods section 3.3i), along with Uj and KAV, were geometric conversion factors that restrict the volumes of interstitial fluid and plasma accessible to macromolecular exchange.

The CSF circulation comprises not only a directed flow of CSF, but in addition a pulsatile to and fro movement throughout the entire brain with local fluid exchange between blood, interstitial fluid, and CSF.

It leads to interstitial fluid accumulation, which may worsen gas exchange, decrease myocardial compliance, limits oxygen diffusion to the tissues, and contributes to metabolic acidosis [ 2, 31].