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Discover Ludwig"interstellar medium" is correct and usable in written English.
You can use it when discussing astronomy and astrophysics, particularly to refer to the matter (such as gas and dust) that exists between the stars in a galaxy. For example, "The interstellar medium of our galaxy is comprised of a variety of elements including hydrogen, helium, and oxygen."
Dictionary
interstellar medium
noun
The matter that exists in the space between star systems in a galaxy, including gas, dust and cosmic rays.
synonyms
Exact(60)
Cox, D. P. The three-phase interstellar medium revisited.
M. Diffuse and dark clouds in the interstellar medium.
The interstellar medium is filled primarily with hydrogen gas.
The interstellar medium is studied by several methods.
Cosmic rays constitute another component of the interstellar medium.
Optical and radio emissions have provided much of the information on the interstellar medium.
B. Consequences of a new hot component of the interstellar medium.
arxiv.org/abs/1101.2032: Planck Early Results: Properties of the interstellar medium in the Galactic plane.
"Someday," he goes on, "someday, somebody will make it to the interstellar medium.
Molecules in the interstellar medium also manifest emissions and absorption lines at radio wavelengths.
Marshall, J. P. et al. Polarization measurements of hot dust stars and the local interstellar medium.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com