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Using intersection strategy can filter the false positive peaks, however intersecting too many peak calling tools may let the unfit tool filter out the good peaks.
Although the intersection strategy has been useful in identifying Mendelian disease genes in the studies cited above, it is not always applicable.
Genes that have divergent calls for the affected sibs would be excluded from further analysis by the intersection strategy described in the Section 1.
Note that the MIN integration fails on this task, since an "intersection" strategy in this context leads to a significant loss of information, thus not allowing to exploit the topological information underlying the entire network.
Moreover, we also compared our integrative model with an intersection strategy that combines PWM scanning with DNase data [ 72] across multiple tissues, a simple method that combines PWM scanning with our DNase model, and an integrative method CENTIPEDE [ 24] that uses PWMs, DNase HS and conservation data.
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When we used the union and the intersection strategies to analysis the peaks of two or three tools, the average precision of intersection (M*C*T) was found to be the most effective method with highest average precision (45.8%) (Table 3 and 4).
The product strategy is also based on quality, in this case the intersection of technical understanding with very high quality woodworking and professional materials, and workmanship.
This course focuses on the intersection of strategy and information technology.
His projects involve the intersection of strategy, organization change, and technology management.
Automating parts of decision-making and product development requires a person that can work at the intersection of strategy, business models, code development, algorithm creation, and product development—a rare breed.
Mr. Young said he had always worked "at the intersection of strategy and content," which was particularly useful for what he described as a coming era where advertiser content would blend "seamlessly" with editorial content.
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