The correlation matrix, in which correlation coefficients are arranged in a matrix consisting of individual elements/isotopes to be correlated to show the correlation coefficient at their intersection cell (Figure 2), shows an overall data structure.
More explicitly, the implications of an intersection between cell-cell adhesion and Wnt pathways are manifold.
Images of dendritic networks (MAP2 staining) were manually converted into graphs (Figure 3a1,2) by implementing a graph deduction paradigm similar to the one used by Shefi et al. [17], where vertices were marked mainly at dendro-dendritic intersections, cell bodies, bifurcations, or growth cones (Figure 3a1,2).
Successful scientists working at the intersection of cell biology and human health are following this recipe for success, too, in slightly different variations.
The discovery that Jarid2 regulates PCP/Wnt signaling in addition to its canonical role in PRC2 highlights an important intersection between cell signaling and chromatin-based regulation, relevant for understanding the interplay between pluripotency and differentiation.
Thus, mTOR operates both upstream and downstream of PKB/AkT, revealing an intricate cross-talk with PKB-dependent survival and mitogenic signaling at the intersection between cell metabolism and regulation of normal tissue growth.
This suggested that the KIND domain of Spire1C might play a role in regulating the extent of ER-mitochondria intersections within cells, and that Spire1CΔKIND-mediated disruption of mitochondrial fission (see Figure 4C, right panel) could be due to a reduction in ER-mediated mitochondrial constriction in these cells (Friedman et al., 2011; Korobova et al., 2013; Murley et al., 2013).
Cell-cell intersection pattern was significantly altered in the mutant with increased 4-lateral intersections in contrast to predominantly 3-lateral intersections in the control (Fig. 4F,G).
The end of lag2 is operationally defined using the cell number curve: it is the intersection of the cells' exponential growth line with the line of initial cell number.
(B ) Bar graph representing the average number of ER-mitochondria intersections per cell.
