Sentence examples for interruption patterns from inspiring English sources
This analysis confirmed that the polyQ-encoding DNA sequence was also interrupted in controls, and, moreover, bore interruption patterns found among the ALS patients.
A different picture might be revealed by characterization of repeat interruption patterns at each SCA locus in that population.
Rozanska et al. [ 89] recently published a large study that complements our results, analyzing repeat lengths and interruption patterns in a normal Polish population.
As has been expertly laid out by Sobczak and Krzyzosiak [ 37] repeat interruption patterns in a given target can differ between populations, even when Q-tract length distributions are similar.
Repeat interruption characteristics are not commonly studied, but reporting overall repeat lengths in the absence of repeat interruption patterns may be quite misleading in studies of allele lengths as they relate to disease prevalence in a given population [ 37, 70, 90].
Juvonen and colleagues [ 70] recently reported that the frequencies of large normal alleles at SCA loci were poor predictors of the prevalence of the respective diseases in Finland but Q-tract lengths were assayed without reporting CAG-tract interruption patterns in different alleles.
The most common repeat numbers were 29 and 30, and the most frequent interruption pattern was 2 or 3 AGGs.
The AGG interruption pattern was deduced from the electropherogram pattern as previously described [ 16], using both parent and child data to reconcile any ambiguities in interpretation.
In addition, the AGG interruption pattern was analyzed in 24 mother-son pairs to investigate the relationship between the AGG structure and characteristics of CGG expansion from mother to child.
There is the status quo, and then its interruption; a pattern, then variation.
In decile 10 and in the VW portfolio, the interruption of the pattern is even larger since Wednesday's average abnormal return is larger than that of both Thursday's and Friday's.
